With Blackburn Rovers the opponents this Saturday, United will be looking to create a gap between themselves and the Lancashire side.
Rovers currently lay two places and one point behind United in the Championship table, and Neil Warnock will be aiming to leave Ewood Park with a larger margin as the race for a Play-Off spot heats up.
"If you look at the bookies odds I'm sure that they will be almost odds on to beat us," said Neil. "Just because of the squad they have.
"We will go into it in good spirits, probably better than we have for a number of games away from home.
"With that kind of atmosphere, we seem to do better in those kind of games so I hope we can do on Saturday.
"I don't worry about who we are playing, it's a matter of trying to take our opportunities and having a bit of luck on the day."
Blackburn is the first of four tough league matches that United face, with Millwall at home and Leicester City and Crystal Palace away to follow this weekend's game.
Playing against clubs that will have their own ambitions of securing a chance at promotion brings its own test and it's one that the United boss will be hoping his team can pass.
"Without the doubt the next four games are probably the toughest of the season," said Warnock. "We've got to try and get as many points as possible.
"When you go to Blackburn, Millwall at home and then Leicester and Palace away I don't think they are going to get much tougher than that.
"We've just got to stick together like we did against Blackpool and try and surprise people.
"We have got a good team spirit at the minute and we've got to try and use that against Blackburn."