LEEDS 1 (Becchio 45+1), TOTTENHAM 3 (Defoe 37, 73, 90+3)
Leeds: Ankergren, Bromby, Michalik, Naylor, Hughes (White 76), Snodgrass, Howson, Doyle, Johnson (Crowe 86), Becchio (Grella 86), Beckford. Subs: A Martin, Robinson, Somma, Hatfield.
Tottenham: Gomes, Corluka, Bassong, Dawson, Bale, Bentley, Huddlestone, Kranjcar, Jenas, Defoe, Crouch. Subs: Palacios, Modric, Rose, Alnwick, Dervite, Parrett, Frederiks.
Referee: A Marriner
Booked: Johnson, Beckford (Leeds), Bentley (Spurs)
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Having picked up a heroic draw at Tottenham 11 days ago, Simon Grayson's men were backed by a full house at Elland Road for the FA Cup fourth round replay.
The original tie had started with the Premier League side taking the game to Leeds, and the replay started in similar fashion. Jermain Defoe should have capitalised on a defensive error inside the first two minutes, David Bentley had a free-kick deflected over the top, and from the resultant corner, Sebastien Bassong blazed over when unmarked.
United were firmly on the back foot and Defoe wasted another decent opportunity when Peter Crouch chested the ball into his path.
It took a full 15 minutes for Leeds to get a foothold in the game and almost immediately, Jermaine Beckford hit the bar with a header, but referee Andre Marriner blew for an infringment.
But the visitors were looking every inch a Premier League outfit with their passing and movement and Casper Ankergren was called upon to make some great saves, the first from point-blank range when advancing off his line, the second a swirling effort from Gareth Bale, and the third from a lively Defoe on 35 minutes following more good passing play.
United's best threat was on the break and Grayson's side looked to move the ball quickly themselves after a Tottenham attack broke down, but the visitors held a good defensive line and Leeds were unable to pick any early holes.
Defoe had proved Tottenham's biggest threat and he fired Tottenham ahead in the 37th minute. David Bentley escaped Andrew Hughes down the flank and Defoe showed good control to turn before delivering an effort into the top corner.
Leeds responded immediately, Lubo Michalik forcing Heurelho Gomes into making a decent save. United's response was good and for the first time in the game it was the visitors who were under pressure and were forced into some good defending as half-time loomed.
But United were level in first half stoppage time, courtesy of a good finish from Luciano Becchio. Leigh Bromby hooked a ball into the box, Beckford's angled shot was well-saved by Gomes, but Becchio showed good instinct to smash home the follow up to level matters.
It had been a cracking opening period, and the second half started off in similar vein, this time Defoe working himself an opening before fizzing a shot over Ankergren's bar. Crouch also touched an effort wide when he got a foot on a powerful drive across goal from Niko Kranjcar.
United's reply was swift and Beckford had a shot deflected wide and a Becchio effort clipped the hand of Michael Dawson for a corner as the game continued at pace.
Dawson was involved at the other when he forced Ankergren into making another save. The goalkeeper was proving United's FA Cup hero and he pulled off another good save to deny Bentley with a strike from distance.
The visitors had the ball in the net on 68 minutes when Defoe converted a low cross from close range, but an offside flag ruled out the attempt.
Defoe wasn't to be denied, though, and he scored his second goal of the night on 73 minutes to give Tottenham the advantage for the fourth time in the tie. Bentley was again the provider and Defoe arrived to slide the ball home to make it 2-1 to Spurs.
United rallied in the hope of levelling yet again, but Tottenham were a quality side on the ball and Crouch went close to adding a third six minutes from time when he hit the bar with a header.
Grayson's side never give up, though, and Bromby headed over the top in the dying moments as Leeds looked for a late goal.
But the tie was settled in the third minute of stoppage when as United threw everyone forward following a free-kick from deep by Ankergren the ball was cleared and Defoe was handed a free charge on the United goal. The Spurs striker composed himself to tuck the ball beyond Ankergren to complete his treble and put the game beyond doubt.